Paper #741

Títol:

A test of the predictive validity of non-linear QALY models using time trade-off utilities

Autors:

José Mª Abellán, José Luis Pinto, Ildefonso Méndez i Xabier Badía

Data:

Febrer 2004

Resum:

This paper presents a test of the predictive validity of various classes of QALY models (i.e., linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO-based QALY calculations may be biased. This bias can be avoided using a power QALY model.

Paraules clau:

Cost-utility analysis, QALYs, power QALY model, predictive validity, time tradeoff, Leex

Codis JEL:

I10, D99

Àrea de Recerca:

Economia Laboral, Pública, de Desenvolupament i de la Salut

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